What we eat, and when, shapes how we age. For 25+ years, we've built the clinical evidence: 40+ published trials across healthy aging and chronic disease.
The evidence
For more than 25 years, we've built our science alongside leading universities and medical centers, including USC's Longevity Institute, Stanford, and Mayo Clinic.
Explore the research →
From research to care
Age is the greatest risk factor for most chronic diseases, from diabetes to cancer, heart disease and Alzheimer's. Our research starts with the body's own programs for repair and renewal—and builds nutrition designed to support them, grounded in peer-reviewed science.
Fasting Mimicking Diet (FMD). Our patented five-day program is designed to activate the body's cellular renewal processes, including autophagy - while you still eat. In a clinical study, three monthly cycles lowered biological age by a median of 2.5 years.
Medical nutrition therapy. Clinician-supervised programs that pair our nutrition technology with dietitian and medical care. In a clinical trial in primary care, adding the FMD to type 2 diabetes care reduced the need for medication and improved glycemic control.
Medically tailored meals. Everyday meals, designed with clinicians, for people living with chronic conditions—32 in all, including kidney disease and autoimmune conditions.
Dr. Longo's research began with a simple question: what controls how a cell ages? Decades of work identified genes and pathways that regulate aging—first in yeast, then in mice, then in human clinical trials. Every product we make follows the same path.
Our science, two ways in
HEALTHCARE
Medical nutrition therapy
L-Nutra Health pairs our patented nutrition technology with lifestyle medicine physicians, longevity-trained dietitians and digital care—clinician-supervised programs for type 2 diabetes, obesity and related conditions.
- •67% reduced medication dependence
- •1.4% average A1C reduction
- •59% reduced insulin resistance
- •Results measured within 6 months
LONGEVITY
Consumer longevity nutrition
Prolon brings the Fasting Mimicking Diet (FMD) home—a plant-based, five-day program shown in clinical studies to support cellular renewal and healthy aging, alongside a line of everyday longevity foods.
- •A median 2.5-year reduction in biological age
- •Visceral fat loss while protecting lean muscle
Founded by a global leader in longevity science
Dr. Valter Longo, Director of the Longevity Institute at the University of Southern California and of the Longevity and Cancer Program at IFOM Milan, founded L-Nutra in 2009. His research has been funded by the National Institutes of Health and the European Union, and his book The Longevity Diet is an international bestseller.
His work on how the body protects and repairs itself during fasting led to the Fasting Mimicking Diet (FMD)—the patented technology at the center of L-Nutra. That research has been conducted in collaboration with institutions including Stanford, Mayo Clinic, Harvard, and UCLA.
Dr. Longo donates 100% of his L-Nutra consulting fees and his book royalties to charity, including the Create Cures Foundation, which supports nutrition education for children and care for patients with advanced disease who can't afford treatment.
L-Nutra Inc
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