Team

 

RESEARCH TEAM LEADERS | SCIENTIFIC BOARD OF ADVISORS | KEY PERSONNELL

 

RESEARCH TEAM LEADERS

 

  • Todd Morgan, Ph.D. - Chief Scientific Officer

    Todd Morgan, PhD, CSO, leads the development of Chemolieve™ and ProLon™ products. He works closely with Dr. Heber and oncology clinicians on the clinical trials to test the efficacy of ChemolieveTM. Dr. Todd Morgan earned his PhD in Biochemistry in 1990 and currently holds an appointment as a Research Professor at the Andrus Gerontology Center in the Davis School of Gerontology of the University of Southern California. His research has been recognized with awards from Alzheimer's Association and the American Federation of Aging Research. He collaborated for many years with Dr. Caleb Finch, one of the world's leading biogerontologist, focusing on studies relating to dietary interventions to delay aging and prevent Alzheimer's diseases in mice and rats. Dr. Morgan collaborates extensively with Dr. Longo in studies focused on fasting, cancer and Alzheimer's Disease. He actively publishes in the leading scientific peer-reviewed journals.

  • Sebastian Brandhorst, Ph.D. - Research Specialist

    Sebastian Brandhorst received his  PhD (Biology) from the University of Duisburg Essen, Germany in March 2013. He compiled his PhD thesis as a graduate student in the laboratory of Dr. Valter Longo in the Davis School of Gerontology at the University of Southern California, USA. His work focuses on pre-clinical research on dietary interventions as novel approaches to increase the efficacy of chemotherapeutic agents in cancer treatment in vitro and in vivo. Recently, Sebastian began to utilize dietary modifications to induce multi-system regeneration and improve the health- and lifespan in rodents.

  • Priya Balasubramanian, Ph.D.

    Priya Balasubramanian, PhD, is a research specialist at L-Nutra. Dr. Balasubramanian received her doctoral degree in Molecular Biology from the University of Southern California in 2010. Her areas of expertise include nutrient sensing pathways, growth hormone/IGF-I signaling and cellular stress resistance. She co-authored a study which reported that growth hormone receptor deficiency (GHRD) is associated with a major reduction in cancer and diabetes in humans and received the Heinz Osterburg prize for doctoral research for her work.

    Dr. Balasubramanian has several years of experience in cellular and in-vitro assays and as part of the scientific team at L-Nutra, she is responsible for overseeing diet design and pre-clinical testing of the diets. She is also actively involved in designing appropriate trials for clinical testing based on the pre-clinical results.

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SCIENTIFIC BOARD OF ADVISORS

L-Nutra is assembling a highly experienced and distinguished scientific and business-oriented Advisory Board to provide invaluable expertise and industry contacts in guiding the organization. Those who have already joined are recognized scientific leaders for their expertise and experience in medical science, drug discovery and development, and in business and entrepreneurship.

  • Valter Longo, Ph.D.

    Valter Longo (Professor of Gerontology) is the founder of L-Nutra and serves as the Chairman of the Scientific Advisory Board. Dr. Longo has won numerous awards for his research, including awards from the Alzheimer's Association and the National Institute on Aging, and raised over $6 million in grant support from the NIH and from private foundations in the past 10 years for research on aging, cancer, and Alzheimer's Disease.

    As an Associate Professor and Hanson Chair of Biogerontology at USC, he directs a laboratory of twenty researchers at the Andrus Gerontology Center, one of the oldest and leading centers for research on aging and age-related diseases in the country. He holds appointments in the Gerontology, Molecular Biology, Integrative and Evolutionary Biology, and Neuroscience departments and is a member of the USC Norris Cancer Center and Alzheimer's Disease Research Center.

    Based on his discovery of the genes and pathways that regulate aging and cellular protection and to the development of a "test tube" system to study aging and resistance to toxins (now adopted by laboratories around the globe), Longo is recognized as one of the pioneers in the genetics and cellular biology of aging fields. Longo's articles have been published in Science, Nature and Cell. In addition to being highly cited (10 articles have been cited more than 100 times), several of Longo's articles have ranked among the most widely read globally.

  • David Heber, MD, Ph.D.

    David Heber is the Director of the UCLA Center for Human Nutrition at the University of California, Los Angeles, a Professor of Medicine and Public Health, the founding Chief of the Division of Clinical Nutrition in the Department of Medicine and the Founding Director of the UCLA Center for Human Nutrition at UCLA. He directs the NCI-funded Clinical Nutrition Research Unit and the NIH Nutrition and Obesity Training Grants at UCLA. Dr. Heber is board-certified in Internal Medicine, and Endocrinology and Metabolism by the American Board of Internal Medicine and in Clinical Nutrition by the American Board of Nutrition. He earned his MD at Harvard Medical School and his PhD in Physiology at the University of California, Los Angeles. Dr. Heber served as a Director of the American Board of Nutrition and past chair of the Education Committee of the American Society of Clinical Nutrition. He is included in the 2000 listing of The Best Doctors in America. Dr. Heber's primary areas of research are obesity treatment and prevention, the role of nutrition, phytochemicals, and botanical dietary supplements in the prevention and treatment of common forms of cancer and cardiovascular disease. He is the author of over 150 peer-reviewed scientific articles, 25 book chapters, 2 professional texts and 4 books for the public.

  • Luigi Fontana, MD, Ph.D.

    Professor Luigi Fontana is a Research Associate Professor in the Department of Internal Medicine of the Division of Geriatrics and Nutritional Science at the Washington University School of Medicine in St. Louis, MO. Prof. Fontana is also the director of the Italian National Institute of Health Nutrition Laboratory. Trained extensively in the fields of internal medicine and metabolism, Fontana is an expert in nutrition, aging and longevity. He has collaborated for over 10 years with one of the world leaders in nutrition and aging, John Holloszy, also of Washington University at St. Louis. His research focuses on the potential role of diet and exercise in retarding the aging process in humans. He is investigating the effects of severe calorie restriction, plant-based diets and endurance exercise on outcomes such as cardiovascular risk factors, inflammation, immune function, glucose tolerance, bone metabolism and quality of life. He is also studying the endocrine role of abdominal fat storage as a mediator of insulin resistance and accelerated aging.

  • Raffaello Vardavas, Ph.D.

    Raffaello Vardavas is a Mathematician at the Rand Corporation in Santa Monica, CA and professor at the Pardee RAND Graduate School. He has a PhD in Physics from Imperial College London, that he obtained in 2002. Between 2002 and 2008 and prior to joining RAND, he worked as a post-doctorate researcher  at UCLA in Mathematics and later in the Bio-Mathematics department.

    His expertise is primarily in constructing and analyzing epidemic models for the spread of infectious disease. Examples include modeling HIV transmission and projecting the impact of test and treat and the emergence of multi drug resistance; modeling scenarios of smalpox bio terroristic attacks and control policy alternatives; modeling the coupled dynamics of seasonal influenza epidemics and vaccination behavior. Other research includes modeling healthcare utilization and cost, the health care reforms of the ACA, supply and maintenance logistics, and evolutionary economics applied to climate change policy. Raffaello is one of the board of directors of L-Nutra since 2009.

  • Fabio Necco, Ph.D.

    Fabio Necco, MSEE  is a senior manager at Fairchild Semiconductor (San Jose, CA). 

    He has more than 16 years’ experience leading product definition and business development in the field of automotive power electronics. He started his career at Magneti Marelli (Turin - Italy) as hardware designer of engine control units. In 2000, Fabio joined International Rectifier (El Segundo, CA) as senior design engineer of inverters for hybrid (gas-electric) vehicles.  He covered various roles from system design to application engineering, including worldwide product and business development for automotive high voltage integrated circuits, as well as high-power switches and smart power.

    He joined Fairchild Semiconductor (San Jose, CA) in 2009, where he is responsible for product definition and development of high power automotive semiconductors with focus on energy efficiency.

    Fabio published several application notes and papers on automotive power semiconductors. He holds 3 patents related to temperature sensing in power modules, advanced packaging, and reverse battery protection. He received his Master’s Degree in Electronic Engineering from Politecnico of Torino (Italy) in 1996 and a certificate in Project Management from UCLA (CA) in 2004.

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    Kurt Hong, MD

     

    Kurt Hong is the Executive Director of the Center for Clinical Nutrition and Applied Health Research at University of Southern California. Dr. Hong earned his MD from the Harvard Medical School and his PhD in Cellular and Molecular Pathology at the University of California, Los Angeles. Dr. Hong is an Associate Professor of Clinical Medicine at USC Keck School of Medicine and a member of the USC Institute for Integrative Health. His research interests include understanding the regulation of adipose stem cells signaling, therapeutics for the Metabolic Syndrome, and nutrient/gut microbiota interactions in obesity and inflammatory bowel disease. Dr. Hong actively publishes in the leading scientific peer-reviewed journals, serves on editorial review boards, and is an expert consultant for several national pharmaceutical companies. He is dual board certified Internal Medicine and Clinical Nutrition and presents frequently at regional and national conferences.  Dr. Hong has twice been named as one of Best Doctors in America®, as chosen by peer-to-peer survey of fellow physicians and winner of Patient’s Choice Award® in 2010 and 2013.



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KEY BUSINESS AND SCIENTIFIC ADVISORS AND CONSULTANTS

L-Nutra is working with key business advisor that possesses expertise in the field of FDA regulation and medical foods and clinical trials auditing (presented in detail below); in IP protection strategy (Hogan & Hartson, Patent Attorney, and Jerry Goldstein Corporate Attorney); in food development and manufacturing (Mishima Food, a food Manufacturer specialized in special foods for hospitals and clinics) and Gaia Nutrition, a food development consulting company. Also, L-Nutra is leveraging the world class expertise of the people listed below:

  • Amy Lee, Ph.D.

    Amy Lee, PhD, is Professor of biochemistry and molecular biology and Associate Director for basic research at the USC/Norris Cancer Center, and a leading expert in cancer research with focus on mechanisms of cancer cell protection. Dr. Lee is serving the American Cancer Society as Scientific Advisory Committee on Institutional Research Grants and the NIH, NCI, as Program Project Review Committee C, Basic and Preclinical Sciences. Among her honor and award to be mentioned the Valedictorian, UC Berkeley, Department of Bacteriology and Immunology; the American Cancer Society Junior Faculty Research Award, the American Cancer Society Faculty Research Award, the NIH/NCI Merit Award (R37) for "Coordinated Gene Expression in Mammalian Cells"; the Judy and Larry Freeman Chair for Cancer Research; the Robert Chandler Award, USC/Norris Comprehensive Cancer Center; the Fellow, American Association for the Advancement of Science (AAAS).

    Dr. Lee earned her MD BA in Bacteriology & Immunology at University of California at Berkeley, California and her MS in Biology and PhD in Biology at California Institute of Technology, California.

  • Francis Richmond, Ph.D.

    Dr. Frances Richmond was educated as a neurophysiologist (BNSc, MSc, PhD) at Queen's University (Kingston, Ontario). She completed post-doctoral studies at the Universite de Montreal and the National Institutes of Health before joining the faculty of Queen's University, where she served as Associate Dean of Life Sciences (1986-1989). She also served as a policy advisor for scientific labor needs at Industry Canada (1990-1992) and as a clinical scientist at the Alfred E. Mann Foundation, an early stage device development group (1994-1995). She was the first female to be appointed Director of a research consortium funded by Canada's Medical Research Council (1995-2000).

    Dr. Richmond joined the faculty of USC in 1999 as Director of Regulatory and Clinical Sciences at the Alfred E. Mann Institute, with a joint appointment in the School of Pharmacy. Her current work includes seven projects in the field of product development which have advanced to the clinical trial stage. Though focused mostly on the BION, an implantable wireless microstimulator, she is also involved in research on other implantables, such as sensors and prosthetic limbs. Dr. Richmond is a member of two large research consortia (NIH Engineering Research partnership and NIH Bioengineering Research partnership) and is Director of the Regulatory Science program, which provides training in the regulatory management of foods, dietary supplements, medical devices and drugs.

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ChemoLieveTM

L-Nutra's first diet to nutritionally manage disease stems from 15 years of research by Prof. Longo at USC. It was largely motivated by the request of many patients who wanted to take advantage of the potential beneficial effects of fasting during cancer treatment but were unable to fast and forego any all meals or and snacks. 

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ProLonTM

ProLon™ is the first Fasting Mimicking Enhancing™ Diet for increased healthspan and reduction of age-related diseases. ProLon™ is also expected to have a potent effect in causing weight loss while optimizing the micronutrient nourishment and promoting anti-aging effects in patients. Given its broader indication and focus on aging and weight management and NOT disease treatment, ProLon™ will be L-Nutra's first product to reach the market. 

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